Mutagenesis in Single-Cells and Evolution (MuSE) 

The generation of variation in the DNA sequence of genomes is a prerequisite for adaptation. Our work complements existing knowledge in the field by addressing the generation of genetic variation and its consequences at the single-cell level, in phages and bacteria.

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Our approach is interdisciplinary and involves the development of new tools that combine genetics, molecular biology, fluorescent microscopy, optogenetics, microfluidics, image analysis  and modelling.